dna

There are those who believe that Yetis exist, most especially Georgians.

All too often when these claims are investigated, though, they turn up a gorilla costume and a couple of rogues.

However, someone is finally bringing scientific credibility to the search not only for Yetis, but also the Loch Ness Monster and, for all I know, unicorns.

Oxford University's Wolfson College has decided to invite every human being in the world to send in samples of animals that appear to be something of a mystery. … Read more

During the H1N1 flu pandemic of 2009, which spread across more than 200 countries and killed more than 18,000 people, it became clear that flu diagnosis was often taking too long and resulting in frequent false negatives.

Today, researchers from Boston University, Harvard, and the Beth Israel Deaconess Medical Center are reporting in the journal PLoS ONE that they have built a microfluidic chip that rivals in accuracy the gold-standard diagnostic test known as RT-PCR but is faster, cheaper, and disposable.

For their four-year study, which involved 146 patients with flu-like symptoms and was funded by the National Institutes … Read more

SUNNYVALE, CALIF., - When it comes to splicing genes and replicating DNA, backrooms and basements are not the most ideal labs. The next wave of home hacking appears to be in biotech, and around the country, a handful of collectives have sprung up in the past few years to accommodate these biohackers.

As the members of a loose-knit biohacking group in the San Francisco Bay Area saw the passion for their homebrew hackers club growing rapidly, they decided it was time to expand. What they eventually built opened late last year as BioCurious, the Bay Area's first hackerspace for … Read more

Engineers at Cornell are building a handheld pathogen detector that will help health care workers around the world test for pathogens such as tuberculosis, gonorrhea, and HIV and get results in as little as 30 minutes, instead of waiting days.

Dan Luo, professor of biological and environmental engineering, has been using synthetic DNA to amplify tiny samples of pathogen DNA, RNA, or proteins. Because of $25 million in funding from the Bill & Melinda Gates Foundation's Grand Challenge to 12 teams developing point-of-care diagnostics, Luo will be combining forces with Edwin Kan, a Cornell professor of electrical and computer engineering, who has built a computer chip that can respond quickly to those amplified samples.

The engineers describe their novel device as something akin to a molecular-level Lego builder.… Read more

Unipro's Ugene is a free bioinformatics modeling and visualization tool. You can use it to visualize, analyze, and annotate DNA and protein sequences. It's widely compatible with a variety of platforms, tools, and methods and includes an integrated Muscle alignment tool, integrated Hmmer2 package, an OpenGL viewer for PDB macromolecular structures, and a custom workflow designer.

Ugene isn't difficult to set up, though much of what it does depends on access to other files and tools. Ugene's functions are based around Projects, Tasks, and Logs. Under Application Settings, we could configure everything from system resource allocation … Read more

It's been a good year for video gamers--and not just the epic legions of Call of Duty fans enjoying Modern Warfare 3.

A few months after Foldit players helped decode the structure of a protein key to the way HIV multiplies, another group of gamers taking on DNA sequencing in the game Phylo have contributed more than 350,000 solutions, the game's designers at McGill University report.

When University of Washington researchers unveiled Foldit in 2008, it wasn't clear whether the protein-folding game would be a one hit wonder. But one-year-old Phylo, already averaging 1,000 eureka … Read more

What does it take to make it to 100 years old? The Archon Genomics X Prize hopes to find out.

As I've researched "extreme" aging in recent years--that is, the genes and lifestyles of centenarians (100 and older) and supercentenarians (110 and older)--a common refrain I hear from my younger peers is, "I don't want to get that old. It sounds miserable."

Whether or not that's true is something most of us will never find out. The reality is that those who make it past 100 are an exceedingly rare breed of … Read more

Researchers at the California Institute of Technology say they have built what they call the world's first artificial neural network out of DNA molecules and that it can answer questions correctly.

Postdoctoral scholar Lulu Qian and colleagues describe "how molecular systems can exhibit autonomous brain-like behaviors" in a paper published about their research in the July 21 issue of the journal Nature.

Taking their cue from the limited intelligence exhibited by single-celled organisms, the researchers built four neurons made up of 112 distinct DNA strands (by contrast, the human brain has some 100 billion neurons).

This rudimentary … Read more

You wouldn't know it by looking at it, but the naked mole-rat has a few things to teach the animal world. It has fascinated researchers since it was discovered a few years ago that the rodents can live for 30 years, compared to the mouse's average life span of four.

So after launching an online database that details the lives and histories of more than 4,000 animal species, a consortium of researchers from around the world set out to sequence the genome of the naked mole-rate--which is native to the deserts of East Africa.

With the help … Read more